Trichomes are specialized epidermal cells located in aerial parts of plants that function in plant defense against biotic and abiotic stresses.The simple unicellular trichomes of Arabidopsis serve as an excellent model to study the molecular mechanism of cell differentiation and pattern formation in plants.Loss-of-function mutations in Arabidopsis
The iceberg technique: an innovative approach for radiofrequency ablation of diving thyroid nodules
Diving thyroid nodules are a limitation of radiofrequency ablation because the mediastinal component cannot be adequately identified by ultrasound (US).We aim to describe a new technique, the iceberg technique, to overcome this issue and explain our three-year experience of using this novel method.The iceberg technique consists of a two-stage treat
Inhibition of Zika virus replication by G-quadruplex-binding ligands
Zika Chargers virus (ZIKV), a mosquito-transmitted Flavivirus, emerged in the last decade causing serious diseases and affecting human health globally.Currently, no licensed vaccines or antivirals are available to combat ZIKV, although several vaccine candidates are in the pipeline.In recent years, the presence of non-canonical G-quadruplex (GQ) se